The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Jan. 04, 2018
Applicant:
Kahr Medical Ltd., Jerusalem, IL;
Inventors:
Noam Shani, Zikhron-Yaakov, IL;
Yosi Gozlan, Rehovot, IL;
Michal Dranitzki Elhalel, Shoresh, IL;
Edwin Bremer, Groningen, NL;
Ido Kaminsky, Ramat-Gan, IL;
Assignee:
KAHR Medical Ltd., Jerusalem, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70596 (2013.01); A61P 35/00 (2018.01); C07K 14/70575 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01);
Abstract
SIRPalpha-CD70 fusion proteins are provided. Accordingly, there is provided a SIRPalpha-CD70 fusion protein comprising a single amino acid linker between the SIRPalpha and the CD70. Also there is provided a SIRPalpha-CD70 fusion protein in a form of at least a homo-trimer. Also provided are polynucleotides and nucleic acid constructs encoding the SIRPalpha-CD70 fusion protein, host-cells expressing the SIRPalpha-CD70 fusion protein and methods of use thereof.