The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 04, 2019
Ustav Organicke Chemie a Biochemie Av Cr, V.v.i., Prague, CZ;
Univerzita Palackeho V Olomouci, Olomouc, CZ;
Lucia Veselovska, Liptovska Luzna, SK;
Michal Hocek, Prague, CZ;
Marian Hajduch, Moravsky Beroun, CZ;
Petr Dzubak, Brodek u Prerova, CZ;
USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., Prague, CZ;
UNIVERZITA PALACKEHO V OLOMOUCI, Olomouc, CZ;
Abstract
Substituted pyridopyrrolopyrimidine ribonucleosides of general formula I, wherein R is as described in the independent claim, preferably R is selected from the group comprising thiophen-3-yl, furan-2-yl, furan-3-yl, benzofuran-2-yl, methylsulfanyl, methoxy, amino, dimethylamino, methyl; and pharmaceutically acceptable salt thereof, their optical isomers and mixtures of such optical isomers. Compounds according to the invention show strong cytostatic and cytotoxic effects on cell lines of tumor origin in a wide variety of diseases including tumors of different histogenetic origin.