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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11299496 B1

PDFFull Text
Date of Patent:
Apr. 12, 2022

Filed:

Jul. 23, 2015

Ligands for alpha-7 nicotinic acetylcholine receptors and methods of treating neurological and inflammatory conditions

Applicants:

Northeastern University, Boston, MA (US);

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Inventors:

Ganeshsingh A. Thakur, Cambridge, MA (US);

Abhijit R. Kulkarni, Boston, MA (US);

Roger Lee Papke, Gainesville, FL (US);

Assignees:

Northeastern University, Boston, MA (US);

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Attorney:

Verrill Dana, LLP

Primary Examiner:

John M Mauro

Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 221/16 (2006.01); C07D 401/04 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 409/10 (2006.01); C07D 409/14 (2006.01); C07D 417/04 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); C07D 221/16 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C07D 409/10 (2013.01); C07D 409/14 (2013.01); C07D 417/04 (2013.01); C07D 491/048 (2013.01);
Abstract

Compounds are provided which bind to an allosteric site on the mammalian alpha-7 nicotinic acetylcholine receptor (alpha-7 nAChR) and act as positive allosteric modulators with or without allosteric agonist activity. The compounds are useful in diagnosing, preventing, or treating a variety of disorders involving cognition, learning, memory, neurodegeneration, drug addiction, inflammation, chronic pain, and neuropathic pain. The compounds also can be used to enhance memory and learning in normal individuals.

Find Patent Forward Citations

Thakur, Ganeshsingh. (2022). Ligands for alpha-7 nicotinic acetylcholine receptors and methods of treating neurological and inflammatory conditions (U.S. Patent No. 11299496). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11299496

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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