The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Nov. 15, 2019
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Andrew Thomas Parsons, Thousand Oaks, CA (US);
Brian McNeil Cochran, Thousand Oaks, CA (US);
William Powazinik, IV, Thousand Oaks, CA (US);
Marc Anthony Caporini, Thousand Oaks, CA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 63/33 (2006.01); C07C 69/76 (2006.01); C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07C 309/24 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07C 69/76 (2013.01); C07C 309/24 (2013.01);
Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as