The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Jan. 25, 2019
Applicant:

Fujimoto Co., Ltd., Matsubara, JP;

Inventors:

Mayumi Watanabe, Matsubara, JP;

Takashi Ando, Matsubara, JP;

Yasuyuki Ueda, Matsubara, JP;

Kenya Matsushita, Matsubara, JP;

Yasuhiko Mizutani, Matsubara, JP;

Jun Takahashi, Matsubara, JP;

Mitsuo Yamada, Matsubara, JP;

Hironori Yokoyama, Matsubara, JP;

Daiki Kanaoka, Matsubara, JP;

Kazunori Urabe, Matsubara, JP;

Takafumi Ishii, Matsubara, JP;

Assignee:

FUJIMOTO CO., LTD., Matsubara, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/14 (2006.01); C07D 413/14 (2006.01); A61P 35/00 (2006.01); A61P 29/00 (2006.01); A61P 37/02 (2006.01); A61P 43/00 (2006.01); A61P 37/00 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/5377 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 409/14 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01);
Abstract

The present invention relates to thiophene derivatives represented by the following formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof, which has TNF-α production suppressive activity and hematologic cancer cell proliferation inhibitory activity, and is useful for the treatment of rheumatoid arthritis, Crohn's disease, ulcerative colitis, and further, hematologic cancer.


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