The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Sep. 30, 2019
Applicant:

Shanghai Longwood Biopharmaceuticals Co., Ltd., Shanghai, CN;

Inventors:

Zhe Wang, Shanghai, CN;

Zhihong Zeng, Shanghai, CN;

Rongzhen Jiang, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/74 (2006.01);
U.S. Cl.
CPC ...
C07D 211/74 (2013.01);
Abstract

The present invention relates to an MDM2 inhabitor, a preparation method therefor, a pharmaceutical composition thereof, and the use thereof specifically, the present invention relates to a compound represented by formula I. The compound has excellent MDM2 inhibitory activities, and can be used for preparing a pharmaceutical composition for treating cancers and other diseases related to MDM2 activities, particularly p53 wild-type cancer.


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