The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Dec. 15, 2017
Applicant:
Memgen, Llc, Houston, TX (US);
Inventor:
Mark J. Cantwell, San Diego, CA (US);
Assignee:
MEMGEN, LLC, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2006.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/42 (2013.01); A61K 38/17 (2013.01); A61P 35/00 (2018.01); C07K 14/70578 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/16032 (2013.01); Y02A 50/30 (2018.01);
Abstract
Disclosed are oncolytic viruses comprising chimeric human/mouse CD40 ligands. The chimeric human/mouse CD40 ligand may be MEM40. The oncolytic virus may be replication competent. The oncolytic virus may be an oncolytic herpes simplex virus. Also disclosed are methods comprising administering an oncolytic virus armed with at least one chimeric human/mouse CD40 ligand, for example MEM40, to a patient suffering from cancer.