The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Aug. 09, 2019
Applicant:

Nantbio, Inc., Culver City, CA (US);

Inventors:

Kayvan Niazi, Culver City, CA (US);

Raymond Wong, Culver City, CA (US);

Peter Sieling, Culver City, CA (US);

Philip T. Liu, Culver City, CA (US);

Assignee:

NantBio, Inc., Culver City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/861 (2006.01); A61K 39/108 (2006.01); A61K 39/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0258 (2013.01); A61K 39/0002 (2013.01); C12N 15/861 (2013.01); A61K 9/0019 (2013.01); A61K 2039/605 (2013.01); C12N 2770/16034 (2013.01);
Abstract

Two-component vaccine formulations and methods are contemplated where the vaccine has an adjuvant component and a therapeutic component. The therapeutic component comprises preferably a recombinant therapeutic virus encoding a therapeutic antigen while the adjuvant component comprises a non-host cell or immune stimulating portion thereof. Notably, use of the adjuvant component will result in significant uptake of the therapeutic component into immune competent cells, even in the absence of receptors for entry of the therapeutic component. In addition, such adjuvant also stimulates expression of the therapeutic antigen.


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