The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Jun. 01, 2016
Applicant:

Temple University—of the Commonwealth System of Higher Education, Philadelphia, PA (US);

Inventors:

Kamel Khalili, Bala Cynwyd, PA (US);

Wenhui Hu, Cherry Hill, NJ (US);

Yonggang Zhang, Maple Shade, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01); A61P 31/18 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61K 48/00 (2013.01); A61P 31/18 (2018.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/1132 (2013.01); C12N 15/907 (2013.01); C12N 2310/10 (2013.01); C12N 2310/20 (2017.05); C12N 2320/11 (2013.01);
Abstract

Compositions for specifically cleaving target sequences in retroviruses include nucleic acids encoding a Clustered Regularly Interspace Short Palindromic Repeat (CRISPR) associated endonuclease and a guide RNA sequence complementary to one or more target nucleic acid sequences in a retrovirus genome.


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