The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 17, 2020
Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd., Fujian, CN;
Huijun Yuan, Fujian, CN;
Tingting Yin, Fujian, CN;
Fei Hong, Fujian, CN;
Juan Yu, Fujian, CN;
Jinxiang Zeng, Fujian, CN;
Shicong Wang, Fujian, CN;
Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd., Fujian, CN;
Abstract
Disclosed is a total flavonoids extract ofKitam., containing 80%-85% of rutin by weight percent content. The results of pharmacological experiments show that the extract can lower the activity of xanthine oxidase in the liver of a hyperuricemia model mouse and reduce the synthesis of uric acid to a certain degree and has a certain uric acid-lowering effect, and can be used as a potential drug for treating hyperuricemia or gout. The method for preparing the total flavonoids extract ofKitam. comprises: after an extraction step, selecting a complex enzyme composed of enzymes with a specific composition and a specific ratio for enzymolosis, and further carrying out the step of extracting and concentrating with macroporous resin and isolating and purifying with macroporous resin, so that the HPLC purity of rutin in the resulting total flavonoids extract ofKitam. reaches 80%-85%.