The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 24, 2016
Applicant:
Kyowa Kirin Co., Ltd., Tokyo, JP;
Inventors:
Kentaro Hatanaka, Tokyo, JP;
Nobuhiro Yagi, Tokyo, JP;
Takeshi Kuboyama, Tokyo, JP;
Kaori Yagi, Tokyo, JP;
Shintaro Hosoe, Tokyo, JP;
Assignee:
KYOWA KIRIN CO., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); C07C 217/28 (2006.01); A61K 9/127 (2006.01); C07D 223/04 (2006.01); C07C 229/12 (2006.01); A61K 31/713 (2006.01); A61P 29/00 (2006.01); C07C 237/22 (2006.01); C07D 401/04 (2006.01); A61K 9/00 (2006.01); C07D 295/088 (2006.01); C07D 207/12 (2006.01); A61P 35/00 (2006.01); C07D 317/28 (2006.01); C07D 211/22 (2006.01); C07D 207/08 (2006.01); C12N 15/11 (2006.01); A61K 31/7088 (2006.01); C07C 211/63 (2006.01); C07C 215/08 (2006.01); C07C 219/08 (2006.01); C07C 229/06 (2006.01); C07C 233/20 (2006.01); C07C 237/08 (2006.01); C07C 271/16 (2006.01); C07D 451/14 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 9/0019 (2013.01); A61K 9/1272 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); C07C 211/63 (2013.01); C07C 215/08 (2013.01); C07C 217/28 (2013.01); C07C 219/08 (2013.01); C07C 229/06 (2013.01); C07C 229/12 (2013.01); C07C 233/20 (2013.01); C07C 237/08 (2013.01); C07C 237/22 (2013.01); C07C 271/16 (2013.01); C07D 207/08 (2013.01); C07D 207/12 (2013.01); C07D 211/22 (2013.01); C07D 223/04 (2013.01); C07D 295/088 (2013.01); C07D 317/28 (2013.01); C07D 401/04 (2013.01); C07D 451/14 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2320/51 (2013.01);
Abstract
The present invention provides nucleic acid-containing lipid nanoparticles containing a lipid (lipid A) which has a hydrophilic unit having a single quaternary ammonium group, and three independent, optionally substituted hydrocarbon groups, a lipid derivative or fatty acid derivative of a water-soluble polymer, and a nucleic acid.