The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

May. 02, 2017
Applicant:

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventors:

John Perentesis, Cincinnati, OH (US);

Bruce Aronow, Cincinnati, OH (US);

Rebekah Karns, Cincinnati, OH (US);

Mayur Sarangdhar, Cincinnati, OH (US);

Assignee:

Children's Hospital Medical Center, Cincinnati, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16H 50/30 (2018.01); A61B 5/00 (2006.01); A61P 35/00 (2006.01); A61K 31/475 (2006.01); A61K 31/573 (2006.01); A61K 31/655 (2006.01); A61K 31/675 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01); A61K 38/14 (2006.01);
U.S. Cl.
CPC ...
G16H 50/30 (2018.01); A61B 5/4848 (2013.01); A61K 31/475 (2013.01); A61K 31/573 (2013.01); A61K 31/655 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 31/7048 (2013.01); A61K 38/14 (2013.01); A61P 35/00 (2018.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/52 (2013.01);
Abstract

Disclosed are methods of treating an individual at risk for a negative outcome associated with a treatment for a disease, in particular a proliferative disorder such as cancer. The method may include the steps of creating a predictive assay that includes both a biomarker and a genetic mutation. The predictive assay indicates the likelihood of a negative outcome associated with a particular treatment in a particular individual, such that an individual may be administered a treatment less likely to be associated with a negative outcome.


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