The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2022
Filed:
Aug. 31, 2018
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Shuguang Zhang, Lexington, MA (US);
Rui Qing, Somerville, MA (US);
Andreas Breitwieser, Vienna, AT;
Uwe Sleytr, Vienna, AT;
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); C07K 14/705 (2006.01); C07K 17/14 (2006.01); C07K 14/32 (2006.01); C07K 14/36 (2006.01); C12N 15/70 (2006.01); G01N 33/551 (2006.01); G01N 33/68 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); C07K 14/32 (2013.01); C07K 14/36 (2013.01); C07K 14/705 (2013.01); C07K 14/7158 (2013.01); C07K 17/14 (2013.01); C12N 15/70 (2013.01); G01N 33/551 (2013.01); G01N 33/6863 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); G01N 2333/7158 (2013.01);
Abstract
The invention includes a bioelectronic interface comprising a self-assembling unit, wherein the self-assembling unit comprises a variant GPCR fusion protein bound to an S-layer fusion protein. The invention also encompasses a biosensor or device comprising the bioelectronic interface and methods of screening for a ligand of a GPCR.