The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

May. 09, 2018
Applicants:

Cambridge Enterprise Limited, Cambridge, GB;

Universidad Politécnica DE Madrid, Madrid, ES;

Inventors:

Andrew Flewitt, Harston, GB;

Girish Rughoobur, Cambridge, MA (US);

Mario De Miguel-Ramos, Cambridge, GB;

Enrique Iborra, Madrid, ES;

Teona Mirea, Madrid, ES;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 29/036 (2006.01); G01N 29/02 (2006.01);
U.S. Cl.
CPC ...
G01N 29/036 (2013.01); G01N 29/022 (2013.01); G01N 2291/0255 (2013.01); G01N 2291/0256 (2013.01); G01N 2291/0426 (2013.01);
Abstract

Disclosed is a method of sensing a target analyte in a liquid sample using a bulk acoustic wave resonator device. The liquid sample is placed on the bulk acoustic wave resonator device which is operated to generate bulk acoustic waves. A shift in the fundamental resonant frequency of the bulk acoustic wave resonator device is measured. The bulk acoustic wave resonator device comprises a resonator structure and an acoustic decoupling layer. The resonator structure comprises: a piezoelectric material layer; electrodes arranged to apply a driving signal to the piezoelectric material layer to generate bulk acoustic waves; and a resonator structure surface. The acoustic decoupling layer is formed over the resonator structure surface. The acoustic decoupling layer acoustic impedance is: up to ⅕ times or not less than 5 times the resonator structure acoustic impedance, and up to ⅕ times or not less than 5 times the liquid sample acoustic impedance.


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