The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

Jul. 19, 2017
Applicant:

Firmenich SA, Geneva, CH;

Inventors:

Michel Schalk, Geneva, CH;

Letizia Rocci, Geneva, CH;

Assignee:

FIRMENICH SA, Satigny, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/62 (2006.01); C12P 5/00 (2006.01); C12P 7/22 (2006.01); C12P 7/26 (2006.01); C12N 9/02 (2006.01); C12N 9/88 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
C12P 7/62 (2013.01); C12N 9/0042 (2013.01); C12N 9/88 (2013.01); C12N 15/70 (2013.01); C12P 5/007 (2013.01); C12P 7/22 (2013.01); C12P 7/26 (2013.01); C12Y 106/02004 (2013.01); C12Y 402/03113 (2015.07);
Abstract

Provided is a method of producing one or more sesquiterpene compounds comprising: contacting an acyclic FPP precursor with a polypeptide having terpene synthase activity, wherein the polypeptide comprises an amino acid sequence that has at least 55% sequence identity to SEQ ID NO: 1, to produce one or more terpenes selected from the group consisting of isovalencene, spirovetiva-1(10),7(11)-diene and valencene or derivatives thereof, or mixture of sesquiterpenes comprising one or more of isovalencene, spirovetiva-1(10),7(11)-diene and/or valencene; and optionally isolating the one or more terpenes or the mixture. Also described is a nucleic acid derived fromencoding a polypeptide having sesquiterpene synthase activity, a polypeptide that can be used to produce one or more sesquiterpenes or a mixture of sesquiterpenes comprising one or more of isovalencene, spirovetiva-1(10),7(11)-diene and/or valencene, and a non-human organism or cell comprising the nucleic acid or comprising an expression vector comprising the nucleic acid.


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