The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2022
Filed:
Dec. 12, 2017
Applicant:
Integrated Dna Techologies, Inc., Coralville, IA (US);
Inventors:
Assignee:
Integrated DNA Technologies, Inc., Coralville, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/90 (2006.01); C12N 9/96 (2006.01); C12N 9/22 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 9/22 (2013.01); C12N 9/96 (2013.01); C12N 15/907 (2013.01); C12N 15/113 (2013.01); C12N 2310/20 (2017.05); C12N 2320/32 (2013.01); C12N 2800/80 (2013.01);
Abstract
This invention pertains to single-stranded carrier nucleic acids and their methods of use for enhancing genome editing ribonucleoprotein complex transfection into cells and the resulting enhancement of CRISPR editing on the target DNA within those cells, as well as introduction of chemical modifications which reduce the integration of the single-stranded carrier nucleic acids at double-stranded breaks.