The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2022
Filed:
Dec. 21, 2018
Gflas Life Sciences, Inc., Seoul, KR;
Seoul National University R&db Foundation, Seoul, KR;
Jongjin Park, Seoul, KR;
Ji Young Yoon, Seoul, KR;
Sunmee Choi, Seoul, KR;
Mijin Park, Seoul, KR;
Slki Park, Seoul, KR;
Aiden Y. Park, Seoul, KR;
Jung Hyuk Lee, Seoul, KR;
Junghak Lim, Seoul, KR;
Dong Wook Kim, Seoul, KR;
Sunghwa Choe, Seoul, KR;
GFLAS LIFE SCIENCES, INC., Seoul, KR;
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, Seoul, KR;
Abstract
The present disclosure provides compositions and methods for increasing mutation efficiency and homologous recombination rates of site-specific endonucleases. The compositions and methods comprise a chimeric polypeptide comprising a site-specific endonuclease or a domain thereof and a functional moiety. The current inventions relate to functional enhancement of the CRISPR-Cas enzymes. Disclosed herein include possible variants and their intended improvements.