The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

May. 19, 2020
Applicant:

Qingdao University, Qingdao, CN;

Inventor:

Shangyong Li, Qingdao, CN;

Assignee:

QINGDAO UNIVERSITY, Qingdao, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); C08B 37/00 (2006.01); B01D 15/38 (2006.01); B01J 20/32 (2006.01); B01J 20/289 (2006.01); B01J 20/26 (2006.01); B01D 15/22 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2402 (2013.01); B01D 15/22 (2013.01); B01D 15/3804 (2013.01); B01J 20/267 (2013.01); B01J 20/289 (2013.01); B01J 20/3212 (2013.01); B01J 20/3251 (2013.01); B01J 20/3255 (2013.01); B01J 20/3274 (2013.01); C08B 37/0039 (2013.01); C12Y 302/01132 (2013.01);
Abstract

The invention relates to a novel biomimetic affinity purification material and its application in the purification of chitosanase, which belongs to the field of industrial biotechnology. The affinity ligand for the biomimetic affinity material is chitodisaccharides, the connecting arm is cyanuric chloride, and the base medium is epoxy-activated Sepharose™ 6B. The desorption constant (Kd) and the theoretical maximum adsorption capacity (Qmax) of the biomimetic affinity material are 24.2 μg/mL and 24.1 mg/g, respectively. Using the above biomimetic affinity material, a chitosanase biomimetic affinity purification method is established, which can produce high-purity chitosanase with high efficiency and low cost, and has good industrial application potential.


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