The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

May. 27, 2016
Applicants:

Universite Du Luxembourg, Luxembourg, LU;

Arizona Board of Regents on Behalf of University of Arizona, Tuscson, AZ (US);

Inventors:

Frederic Zenhausern, Fountain Hills, AZ (US);

Paul Wilmes, Bettembourg, LU;

Pranjul Shah, Esch-sur-Alzette, LU;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); C12M 1/00 (2006.01); C12M 1/42 (2006.01); C12M 3/04 (2006.01); C12M 3/00 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); C12M 3/04 (2013.01); C12M 3/065 (2013.01); C12M 21/08 (2013.01); C12M 23/06 (2013.01); C12M 29/04 (2013.01); C12M 29/12 (2013.01); C12M 35/08 (2013.01);
Abstract

Cell culture apparatus for emulating gastrointestinal tract conditions and comprising at least two adjacent, microfluidic, cell cultivation channels separated by a permeable or semipermeable membrane, a first channel carrying gastrointestinal tract epithelial cells or tissues and a second channel carrying luminal and preferably mucosal microbiota, and wherein said second channel comprises one or more dwell chambers capable of providing a location for unattached luminal flora to reside away from any direct flow in said second channel, permits modelling of multiple sections of the gastrointestinal tract and control of retention times.


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