The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2022
Filed:
Jun. 29, 2017
Applicant:
Blade Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Brad Owen Buckman, Oakland, CA (US);
Shendong Yuan, San Ramon, CA (US);
John Beamond Nicholas, Redwood City, CA (US);
Jingyuan Ma, Palo Alto, CA (US);
Kumaraswamy Emayan, Albany, CA (US);
Marc Adler, Orinda, CA (US);
Assignee:
Blade Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/18 (2006.01); A61P 1/16 (2006.01); A61P 13/12 (2006.01); A61P 11/00 (2006.01); C07D 245/06 (2006.01); C07D 267/00 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01); C07D 413/12 (2006.01); C07D 471/18 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/18 (2013.01); A61P 1/16 (2018.01); A61P 11/00 (2018.01); A61P 13/12 (2018.01); C07D 245/06 (2013.01); C07D 267/00 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 413/12 (2013.01); C07D 471/18 (2013.01); C07D 498/04 (2013.01);
Abstract
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to macrocyclic α-keto amide derivatives and their use as therapeutic agents.