The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

Jan. 18, 2019
Applicant:

Sichuan Kelun-biotech Biopharmaceutical Co., Ltd., Sichuan, CN;

Inventors:

Shuai Song, Sichuan, CN;

Qiang Tian, Sichuan, CN;

Yongyong Wu, Sichuan, CN;

Mingliang Zhao, Sichuan, CN;

Chaolei Wang, Sichuan, CN;

Jiaqiang Cai, Sichuan, CN;

Lichun Wang, Sichuan, CN;

Jingyi Wang, Sichuan, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61P 1/16 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61P 1/16 (2018.01);
Abstract

Related is a nitrogen-containing benzoheterocycle compound containing a carboxylic acid group as shown in general formula (I), or a stereoisomer or pharmaceutically acceptable salt thereof. The compound has excellent pharmacokinetic properties and extremely remarkable liver targeting properties, and a pharmaceutical composition comprising the same may be used as a CCR antagonist, in particular a CCR2 and/or CCR5 antagonist and can be used in mediated disease, including, but not limited to, nonalcoholic fatty liver disease (NAFLD) or the like.


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