The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2022
Filed:
Dec. 16, 2017
Reata Pharmaceuticals, Inc., Irving, TX (US);
Xin Jiang, Coppell, TX (US);
Christopher F. Bender, Garland, TX (US);
Melean Visnick, Irving, TX (US);
Martha R. Hotema, Hurst, TX (US);
Zachary S. Sheldon, Dallas, TX (US);
Chitase Lee, Ann Arbor, MI (US);
Bradley William Caprathe, Livonia, MI (US);
Gary Bolton, Ann Arbor, MI (US);
Brian Kornberg, Ann Arbor, MI (US);
REATA PHARMACEUTICALS, INC., Irving, TX (US);
Abstract
Disclosed herein are compounds of the formulas: as well as analogs thereof, wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used to inhibit RORγ and/or reduce the expression of IL-17. Also provided are methods of administering compounds and composition provided herein to a patient in need thereof, for example, for the treatment or prevention of diseases or disorders associated with inflammation or autoimmune disorders.