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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11292237 B1

PDFFull Text
Date of Patent:
Apr. 05, 2022

Filed:

Sep. 13, 2019

Microfluidic assay assemblies and methods of manufacture

Applicant:

Cyvek, Inc., Wallingford, CT (US);

Inventor:

Martin A. Putnam, Cheshire, CT (US);

Assignee:

CYVEK, INC., Wallingford, CT (US);

Attorney:

McCormick, Paulding & Huber PLLC

Primary Examiner:

Jeffry H Aftergut

Assistant Examiner:

Jaeyun Lee

Int. Cl.
CPC ...
B32B 37/10 (2006.01); B32B 37/00 (2006.01); B32B 37/02 (2006.01); B01L 3/00 (2006.01); G01N 21/05 (2006.01); G01N 21/64 (2006.01); G01N 33/543 (2006.01); G01N 21/03 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
B32B 37/1009 (2013.01); B01L 3/502707 (2013.01); B32B 37/0076 (2013.01); B32B 37/02 (2013.01); G01N 21/05 (2013.01); G01N 21/645 (2013.01); G01N 33/54366 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/16 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/168 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0638 (2013.01); B01L 2400/086 (2013.01); G01N 2021/0346 (2013.01); G01N 2021/058 (2013.01); G01N 2035/00158 (2013.01); Y10T 29/494 (2015.01); Y10T 156/10 (2015.01);
Abstract

A method of making at least a portion of at least one microfluidic actuator having a flexible diaphragm portion and an opposite surface portion, the diaphragm and opposite surface each having opposed faces, at least one of the faces comprising surface-activated PDMS, and the opposed faces being arranged such that when the opposed faces contact each other, they form a fluidic seal, including performing repeated make-and-break-contact protocol on the contacting opposed faces until the tendency for permanent bonds to form between the contacting faces has been neutralized, thereby enabling the diaphragm portion to perform actuated movements to engage and disengage with the opposite surface portion, without the diaphragm sticking to the opposite surface portion.

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