The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

Apr. 29, 2019
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Cameron McIntyre, Lakewood, OH (US);

Nicholas Maling, Cleveland, OH (US);

Scott Lempka, Cleveland, OH (US);

Assignee:

Case Western Reserve University, Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 1/05 (2006.01); A61N 1/36 (2006.01); G16H 20/30 (2018.01); A61B 5/055 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61N 1/0534 (2013.01); A61N 1/36064 (2013.01); A61N 1/36082 (2013.01); A61B 5/055 (2013.01); A61B 5/4064 (2013.01); A61N 1/36185 (2013.01); G16H 20/30 (2018.01);
Abstract

Embodiments discussed herein facilitate identification of a target area within a region of a brain for stimulation via one or more BS (Brain Stimulation) electrodes. One example embodiment comprises generating, based on radiological imaging of a region of a brain of a patient and BS electrode lead(s), a patient-specific anatomical model of the region and lead(s); populating the patient-specific anatomical model with neuron models based on associated neuronal densities of at least one of the region or one or more sub-regions of the region; constructing a patient-specific local field potential (LFP) model of the region based on the patient-specific anatomical model and location(s)/orientation(s) of the one or more BS electrode leads; and identifying, via the patient-specific LFP model of the region, a target area within the region for at least one of monitoring or treatment of a medical condition via the one or more BS electrode leads.


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