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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11291722 B1

PDFFull Text
Date of Patent:
Apr. 05, 2022

Filed:

Jul. 11, 2017

Vaccine composition comprising cyclic peptides, antibodies to the cyclic peptides or an anticancer composition comprising the same

Applicant:

Industry Academic Cooperation Foundation, Hallym University, Chuncheon-si, KR;

Inventors:

Hyung Joo Kwon, Cheongju-si, KR;

Yong Sung Kim, Suwon-si, KR;

Assignee:

INDUSTRY ACADEMIC COOPERATION FOUNDATION HALLYM UNIVERSITY, Chuncheon-si, KR;

Attorney:
Primary Examiner:

Nelson B Moseley, II

Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/395 (2006.01); G01N 33/574 (2006.01); C07K 16/18 (2006.01); A61P 35/04 (2006.01); A61K 39/00 (2006.01); A61K 9/127 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 9/127 (2013.01); A61K 39/001102 (2018.08); A61K 39/395 (2013.01); A61P 35/04 (2018.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); G01N 33/574 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/572 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); G01N 2333/705 (2013.01);
Abstract

The present invention relates to a vaccine composition comprising cyclic peptides of the present invention, antibodies to cyclic peptides, or an anticancer composition comprising them, and the vaccine composition of the present invention exhibit an inhibitory activity for metastasis of cancer. In addition, the antibodies of the present invention bind to the tumor-specific antigen TM4SF5 with high affinity, and significantly inhibit the growth, metastasis and invasion of cancer cells expressing the tumor-specific antigen TM4SF5, and thus can be used for diagnosis, prevention or treatment of various cancers expressing TM4SF5.

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