The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

Dec. 10, 2019
Applicant:

Korea Center for Disease Control and Prevention, Chungcheongbuk-do, KR;

Inventors:

You-Jin Kim, Chungcheongbuk-do, KR;

Hyun Ju In, Chungcheongbuk-do, KR;

HeeJi Lim, Chungcheongbuk-do, KR;

Sun-Dong Jang, Chungcheongbuk-do, KR;

Jung-Sik Yoo, Chungcheongbuk-do, KR;

Gyung Tae Chung, Chungcheongbuk-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); C07K 16/10 (2006.01); C12N 15/70 (2006.01); C12N 1/20 (2006.01); A61K 39/00 (2006.01); C12R 1/19 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); C07K 16/1081 (2013.01); C12N 1/205 (2021.05); C12N 7/00 (2013.01); C12N 15/70 (2013.01); A61K 2039/575 (2013.01); C07K 2317/76 (2013.01); C12N 2770/24122 (2013.01); C12N 2770/24134 (2013.01); C12R 2001/19 (2021.05);
Abstract

The present invention relates to a recombinant antigen derived from Zika virus E protein and use thereof. Specifically, the present invention provides a polynucleotide encoding Zika virus E protein domain III alone or repeatedly three times, a recombinant plasmid vector comprising the polynucleotide, and a DNA vaccine composition that may induce an immune response to Zika virus by expressing a Zika virus antigen protein effectively. In addition, the present invention provides a neutralizing antibody against Zika virus obtained using the polynucleotide and a method for preparing the neutralizing antibody.


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