The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2022

Filed:

Nov. 03, 2016
Applicant:

Prometic Biotherapeutics, Inc., Rockville, MD (US);

Inventors:

Martin Robitaille, Saint-Colomban, CA;

Karen Thibaudeau, Rosemere, CA;

Pierre Laurin, Ville Mont-Royal, CA;

Stacy Plum, Arlington, VA (US);

Assignee:

PROMETIC BIOTHERAPEUTICS, INC., Rockville, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C12N 9/68 (2006.01); A61P 3/00 (2006.01); A61P 9/00 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/484 (2013.01); A61P 3/00 (2018.01); A61P 9/00 (2018.01); A61P 29/00 (2018.01); C12N 9/6435 (2013.01); C12Y 304/21007 (2013.01);
Abstract

Subjects of the invention are a method of plasminogen supplementation in a plasminogen-deficient subject, and method for the treatment of plasminogen-deficiency in a plasminogen-deficient subject. These methods comprise administering to the plasminogen-deficient subject a dose of plasminogen, and more particularly Glu-plasminogen, for increasing the subject plasminogen activity level by at least about 1%, and more particularly by at least 10%, of the normal plasminogen activity and for maintaining the plasminogen activity level over a supplementation period or a treatment period. The plasminogen-deficient subject of the present invention may suffer from Type-I, Type-II plasminogen-deficiency or an acquired deficiency.


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