The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2022
Filed:
Apr. 20, 2017
Applicants:
Centro DE Investigaciones Energéticas, Medioambientales Y Tecnológicas, O.a., M.p., Madrid, ES;
Fundación Instituto DE Investigación Sanitaria Fundación Jiménez Diaz, Madrid, ES;
Consorcio Centro DE Investigación Biomédica En Red, M.p., Madrid, ES;
Inventors:
Jose C. Segovia, Madrid, ES;
Maria G. Gomez, London, GB;
Susana Navarro, Madrid, ES;
Nestor Meza, San Cristobal, VE;
Juan Bueren, Madrid, ES;
Maria G. Bravo, Madrid, ES;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/86 (2006.01); A61K 35/28 (2015.01); A61K 48/00 (2006.01); C12N 5/078 (2010.01); C12N 9/12 (2006.01); C12N 15/79 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 35/28 (2013.01); A61K 48/005 (2013.01); C12N 5/0641 (2013.01); C12N 9/1205 (2013.01); C12N 15/63 (2013.01); C12Y 207/0104 (2013.01); C12N 15/79 (2013.01); C12N 2510/00 (2013.01); C12N 2740/16043 (2013.01); C12N 2800/22 (2013.01); C12N 2830/48 (2013.01);
Abstract
The present disclosure provides polynucleotide cassettes, expression vectors and methods for the expression of a gene in mammalian cells to provide gene therapy for pyruvate kinase deficiency.