The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2022
Filed:
Oct. 15, 2020
Applicant:
Wigen Biomedicine Technology (Shanghai) Co., Ltd., Shanghai, CN;
Inventors:
Houxing Fan, Shanghai, CN;
Yuli Xie, Shanghai, CN;
Assignee:
WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD., Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 491/00 (2006.01); C07D 471/10 (2006.01); C07D 471/08 (2006.01); C07D 471/04 (2006.01); C07D 413/12 (2006.01); C07D 487/04 (2006.01); A61P 35/04 (2006.01); C07D 403/14 (2006.01); C07D 487/10 (2006.01); C07D 491/107 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61P 35/04 (2018.01); C07D 403/14 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 491/107 (2013.01); A61K 9/0053 (2013.01); C07B 2200/07 (2013.01); C07B 2200/13 (2013.01);
Abstract
The invention relates to a series of novel compounds containing acryloyl group. In particular, the invention relates to acryloyl group-containing compounds shown in formula (1) and the preparation method thereof, and application of the compounds shown in formula (1) and pharmaceutically acceptable salts thereof in preparation of medicaments for treating, regulating and/or preventing diseases related to physiological conditions related to CRM1 protein.