The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2022

Filed:

Sep. 21, 2018
Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Regan James Thomson, Chicago, IL (US);

Emily E. Robinson, Chicago, IL (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/617 (2006.01); C07C 49/788 (2006.01); C07C 45/67 (2006.01); C07C 49/792 (2006.01); C07D 303/32 (2006.01); C07D 313/10 (2006.01); C07C 49/453 (2006.01); C07C 49/757 (2006.01); C07C 49/643 (2006.01);
U.S. Cl.
CPC ...
C07C 49/788 (2013.01); C07C 45/673 (2013.01); C07C 49/453 (2013.01); C07C 49/643 (2013.01); C07C 49/757 (2013.01); C07C 49/792 (2013.01); C07D 303/32 (2013.01); C07D 313/10 (2013.01); C07B 2200/07 (2013.01); C07C 2603/26 (2017.05); C07C 2603/32 (2017.05); C07C 2603/36 (2017.05); C07C 2603/50 (2017.05); C07C 2603/94 (2017.05);
Abstract

Disclosed are new polycyclic carbogenic molecules and their methods of synthesis. The new polycyclic carbogenic molecules may be utilized in anti-cancer therapies. In particular, the polycyclic carbogenic molecules may be formulated as pharmaceutical compositions that comprise the small molecules, which compositions may be administered in methods of treating and/or preventing cell proliferative diseases and disorders such as cancer. The new polycyclic carbogenic molecules may be prepared from vinyl- or allyl-substituted cyclohexenone precursors via preparation of a silyl bis-enol ether intermediate.


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