The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2022
Filed:
Apr. 03, 2018
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Laura Codarri Deak, Schlieren, CH;
Jens Fischer, Penzburg, DE;
Sabine Imhof-Jung, Penzberg, DE;
Christian Klein, Schlieren, CH;
Stefan Seeber, Penzberg, DE;
Patrick Alexander Aaron Weber, Schlieren, CH;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 35/17 (2013.01); A61K 39/001102 (2018.08); A61P 31/12 (2018.01); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); C07K 16/2809 (2013.01); C07K 16/2818 (2013.01); C07K 16/3007 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2300/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/522 (2013.01); C07K 2317/526 (2013.01); C07K 2317/55 (2013.01); C07K 2317/64 (2013.01); C07K 2317/66 (2013.01); C07K 2317/71 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/74 (2013.01); C07K 2319/75 (2013.01);
Abstract
The invention relates to bispecific antibodies comprising a first antigen binding domain that specifically binds to PD1 and a second antigen binding domain that specifically binds to LAG3. The invention further relates to methods of producing these molecules and to methods of using the same.