The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2022
Filed:
Feb. 11, 2020
Applicants:
Institut Pasteur DE Lille, Lille, FR;
Institut National DE LA Santé ET DE LA Recherche Médicale (Inserm), Paris, FR;
Inventors:
Camille Locht, Brussels, BE;
Nathalie Mielcarek, Blandain, BE;
Anne-Sophie Debrie, La Madeleine, FR;
Dominique Raze, Gruson, FR;
Julie Bertout, Pont-à-Marcq, FR;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/099 (2013.01); A61K 2039/522 (2013.01); A61K 2039/523 (2013.01); A61K 2039/543 (2013.01);
Abstract
A mutatedstrain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutatedstrain can be used in an immunogenic composition or a vaccine for the treatment or prevention of ainfection. Use of the attenuatedstrain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection byare also provided.