The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2022

Filed:

Oct. 16, 2015
Applicant:

Sentiss Pharma Private Limited, New Delhi, IN;

Inventors:

Mandar V. Shah, New Delhi, IN;

Deepak Bahri, New Delhi, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5575 (2006.01); A61K 47/26 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 47/34 (2017.01); A61K 31/5377 (2006.01); A61K 31/542 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5575 (2013.01); A61K 9/0048 (2013.01); A61K 31/5377 (2013.01); A61K 31/542 (2013.01); A61K 45/06 (2013.01); A61K 47/26 (2013.01); A61K 47/34 (2013.01); A61K 2300/00 (2013.01);
Abstract

Disclosed herein an ophthalmic formulation comprises carbonic anhydrase inhibitor(s) alone, in an aqueous solution or a combination of two intraocular pressure (IOP) reducing and/or glaucoma treatment agents or a combination of three intraocular pressure (IOP) reducing and/or glaucoma treatment agents and a manufacturing process thereof. The present invention further relates to the composition(s) manufactured by the process described herein and methods for treating persons suffering from glaucoma or ocular hypertension. In particular, the persons are treated with carbonic anhydrase inhibitor(s) alone or a combination of two intraocular pressure (IOP) reducing and/or glaucoma treatment agents or a combination of three intraocular pressure (IOP) reducing and/or glaucoma treatment agents to control their intraocular pressure (IOP). Further disclosed herein the formulations as manufactured relate to a highly solubilized form of poorly insoluble drugs/active ingredient(s) to improve its bio-availability and manufacturability.


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