The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2022

Filed:

Sep. 17, 2019
Applicant:

Sinew Pharma Inc., Taipei, TW;

Inventors:

Oliver Yoa-Pu Hu, Taipei, TW;

Tung-Yuan Shih, Taipei, TW;

Cheng-Huei Hsiong, Taipei, TW;

Hsin-Tien Ho, Taipei, TW;

Assignee:

SINEW PHARMA INC., Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/225 (2006.01); C07C 69/63 (2006.01); A61K 31/194 (2006.01); A61K 45/06 (2006.01); C07D 319/06 (2006.01); C07D 407/12 (2006.01); C07C 69/42 (2006.01); C07H 13/04 (2006.01); C07C 51/215 (2006.01); A61P 1/16 (2006.01); A61K 47/26 (2006.01); A61K 31/047 (2006.01); A61K 31/428 (2006.01); A61K 31/7004 (2006.01);
U.S. Cl.
CPC ...
A61K 31/194 (2013.01); A61K 45/06 (2013.01); A61K 47/26 (2013.01); A61P 1/16 (2018.01); C07C 51/215 (2013.01); C07C 69/42 (2013.01); C07D 319/06 (2013.01); C07D 407/12 (2013.01); C07H 13/04 (2013.01); A61K 31/047 (2013.01); A61K 31/428 (2013.01); A61K 31/7004 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. The present compound is represented by Formula (II), which has the formula: R—O—X—(CH)—X—O—R, wherein: each X is —C(═O)—; Ris a C-Calkyl polyol: Ris a saccharide group of formula (G); G is a monosaccharide residue, where (i) at least one of the —OH groups in (G)is substituted by a halogen atom, and (ii) the saccharide group of formula (G)is linked to —O— through a —CHgroup; p is 1 or 2; and m is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10.


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