The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2022

Filed:

Dec. 07, 2016
Applicants:

Koninklijke Philips N.v., Eindhoven, NL;

Bracco Suisse SA, Manno, CH;

Inventors:

Scott William Dianis, Andover, MA (US);

Jeffry Earl Powers, Bainbridge Island, WA (US);

Ralf Seip, Carmel, NY (US);

William Tao Shi, Cambridge, MA (US);

Yannick Bohren, Plan Les Ouates, CH;

Emmanuel Jean-Marie Gaud, La Croix-de-Rozon, CH;

Jean-Marc Paul Robert Hyvelin, Geneva, CH;

Assignee:

KONINKLIJKE PHILIPS N.V., Eindhoven, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 17/22 (2006.01); A61B 8/06 (2006.01); A61B 8/14 (2006.01); A61B 8/08 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/22004 (2013.01); A61B 8/06 (2013.01); A61B 8/14 (2013.01); A61B 8/488 (2013.01); A61B 2017/00106 (2013.01); A61B 2017/22008 (2013.01); A61B 2017/22028 (2013.01);
Abstract

A therapeutic ultrasound system transmits a staggered or interleaved pattern of therapy beams for use in sonothrombolysis and other Vascular Acoustic Resonators (VAR) mediated therapy. The inventive technique minimizes VAR, e.g. microbubble, destruction due to adjacent beams, ensures uniform sonication of the targeted region by filling in the spaces between the beams in subsequent passes, and further provides a means for bubble replenishment to maximize the clot lysis from ultrasound. The technique is also applicable to diagnostic ultrasound, VAR mediated drug delivery and blood brain barrier opening.


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