The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2022

Filed:

Aug. 31, 2018
Applicant:

Terumo Kabushiki Kaisha, Tokyo, JP;

Inventors:

Nozomi Ami, Kanagawa, JP;

Shigeru Tamatsukuri, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61K 49/00 (2006.01); A61K 9/00 (2006.01); A61B 5/0492 (2006.01); G01N 33/483 (2006.01); A61B 5/296 (2021.01); A61B 5/389 (2021.01); A61D 7/04 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4824 (2013.01); A61B 5/296 (2021.01); A61B 5/389 (2021.01); A61B 5/4848 (2013.01); A61B 5/6838 (2013.01); A61B 5/6846 (2013.01); A61K 9/0019 (2013.01); A61K 49/0008 (2013.01); G01N 33/483 (2013.01); A61B 5/6884 (2013.01); A61B 2503/40 (2013.01); A61B 2503/42 (2013.01); A61D 7/04 (2013.01);
Abstract

A method for assessing pain caused by administration of a drug solution includes: anesthetizing an experimental animal; inserting a measurement electrode into skeletal muscle of the anesthetized experimental animal; puncturing an injection needle into a predetermined part of the anesthetized experimental animal while measuring a myoelectric potential of the skeletal muscle with the measurement electrode; administering a drug solution to the anesthetized experimental animal; and (i) measuring a duration time of the myoelectric response caused by the administration of the drug solution, and/or (ii) measuring an EMG intensity obtained by integrating absolute values of myoelectric potentials during a period from occurrence of the myoelectric response by the administration of the drug solution to disappearance of the myoelectric response.


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