The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2022
Filed:
Sep. 01, 2016
Applicant:
Denovo Biopharma Llc, San Diego, CA (US);
Inventors:
Douglas J. Jolly, Encinitas, CA (US);
Amy H. Lin, San Diego, CA (US);
Andrew Hofacre, Laguna Niguel, CA (US);
Daniel J. Hogan, San Diego, CA (US);
Derek G. Ostertag, San Diego, CA (US);
Assignee:
DENOVO BIOPHARMA LLC, San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 48/00 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01); C07K 14/535 (2006.01); C07K 14/705 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 48/005 (2013.01); A61P 35/00 (2018.01); C07K 14/535 (2013.01); C07K 14/70507 (2013.01); C07K 16/2827 (2013.01); A61K 48/00 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); C07K 2319/50 (2013.01); C07K 2319/60 (2013.01); C07K 2319/75 (2013.01); C12N 15/1138 (2013.01); C12N 2310/141 (2013.01); C12N 2740/13021 (2013.01); C12N 2740/13022 (2013.01); C12N 2740/13043 (2013.01); C12N 2840/20 (2013.01); C12N 2840/203 (2013.01);
Abstract
This disclosure provides modified recombinant retroviruses comprisings containing a 2A-peptide or peptide-like coding sequence operably linked to a heterologous polynucleotide. The disclosure further relates to cells and vector expressing or comprising such vectors and methods of using such modified vectors in the treatment of disease and disorders.