The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2022
Filed:
Apr. 04, 2016
Applicant:
Precision Biologics, Inc., Rockville, MD (US);
Inventor:
Philip M. Arlen, Great Neck, NY (US);
Assignee:
PRECISION BIOLOGICS, INC., Rockville, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/303 (2013.01); C07K 16/3015 (2013.01); C07K 16/3023 (2013.01); C07K 16/3046 (2013.01); C07K 16/3069 (2013.01); A61N 2005/109 (2013.01); A61N 2005/1021 (2013.01); A61N 2005/1087 (2013.01); A61N 2005/1089 (2013.01); A61N 2005/1098 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01);
Abstract
This invention relates to antibodies to anti-cancer antibodies and uses thereof, including combination therapies and compositions. Combinations targeting the extrinsic, intrinsic, or common pro-apoptotic pathways are provided. Exemplary anti-cancer antibodies are differentially expressed in cancers, such as antibodies targeting the bind the antigens NPC-1, 16C3, or 31.1. Exemplary anti-cancer antibodies target lung cancer, ovarian cancer, cervical cancer, uterine cancer, pancreas cancer, breast cancer, and colon cancer.