The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2022
Filed:
Mar. 12, 2020
Genentech, Inc., South San Francisco, CA (US);
Emily J. Hanan, South San Francisco, CA (US);
Georgette Castanedo, South San Francisco, CA (US);
Marie Gabrielle Braun, South San Francisco, CA (US);
Keira Garland, South San Francisco, CA (US);
Peter Andrew Smith, South San Francisco, CA (US);
Richard Pastor, South San Francisco, CA (US);
Paul Gibbons, South San Francisco, CA (US);
Yunxing Cheng, Beijing, CN;
Guosheng Wu, Beijing, CN;
Yuhong Fu, Beijing, CN;
Po-Wai Yuen, Beijing, CN;
Genentech, Inc., South San Francisco, CA (US);
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of lipoprotein signal peptidase II (LspA), a key protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.