The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2022

Filed:

Sep. 04, 2018
Applicant:

Bioardis Llc, San Diego, CA (US);

Inventors:

Ning Shao, Beijing, CN;

Ding Wang, Beijing, CN;

Hongbin Yuan, Shanghai, CN;

Frank Kayser, San Francisco, CA (US);

Assignee:

BIOARDIS LLC, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/10 (2006.01); A61P 35/04 (2006.01); C07D 231/12 (2006.01); C07D 231/38 (2006.01); C07D 231/54 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/10 (2013.01); A61P 35/04 (2018.01); C07D 231/12 (2013.01); C07D 231/38 (2013.01); C07D 231/54 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 471/04 (2013.01);
Abstract

An aromatic derivative as represented by formula (I), a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising same, a preparation method therefor, and uses of the aromatic derivative and the pharmaceutically acceptable salt thereof or the pharmaceutical composition comprising same in preparing a therapeutic agent, specifically an FGFR4 tyrosine kinase inhibitor, and in preparing a medicament for treating and/or preventing neoplastic and inflammatory diseases. The substituents of formula (I) are same as defined in the description.


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