The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2022

Filed:

Mar. 19, 2019
Applicant:

Novavax, Inc., Gaithersburg, MD (US);

Inventors:

Sarathi Boddapati, Germantown, MD (US);

Anushree Herwadkar, Clarksburg, MD (US);

Jason Wong, Rockville, MD (US);

Yen-Huei Lin, Rockville, MD (US);

Gale Smith, Germantown, MD (US);

Jing-Hui Tian, Germantown, MD (US);

Assignee:

Novavax, Inc., Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); A61P 31/16 (2006.01); A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 9/0051 (2013.01); A61K 9/51 (2013.01); A61P 31/16 (2018.01); A61K 2039/70 (2013.01);
Abstract

Disclosed herein are multivalent nanoparticle vaccine compositions suitable for use in influenza vaccines. The nanoparticles include effective amounts of influenza glycoproteins that provide increased immune responses compared to a commercially available influenza vaccine composition. The present disclosure also provides vaccine formulation strategies that are cost effective and are convenient for clinical use. Methods of administering the nanoparticle vaccine compositions to a subject are also disclosed.


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