The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2022

Filed:

Sep. 21, 2016
Applicants:

Assistance Publique—hopitaux DE Paris, Paris, FR;

Universite DE Paris, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Médicale (Inserm, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Jean-Philippe Wolf, Paris, FR;

Anne Lombes, Paris, FR;

Morgane Bomsel, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); B63B 21/00 (2006.01); A61K 8/64 (2006.01); C07K 14/705 (2006.01); C07K 7/64 (2006.01); C07K 5/087 (2006.01); A61P 15/08 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/12 (2013.01); A61K 8/64 (2013.01); A61K 9/0014 (2013.01); A61K 9/0048 (2013.01); A61P 15/08 (2018.01); B63B 21/00 (2013.01); C07K 5/0812 (2013.01); C07K 7/64 (2013.01); C07K 14/705 (2013.01); B63B 2021/004 (2013.01);
Abstract

The present invention relates to the use of a cyclic peptide comprising the tripeptide reproducing a binding site of fertilin beta to the oocyte integrin, for improving cellular energy metabolism. More particularly, the invention concerns the use of a cyclic peptide comprising the tripeptide FEEc for stimulating the energy metabolism of gametes or embryonic cells in the context of medically assisted procreation (MAP) protocols, in particular promoting the in vitro maturation of the oocyte, the fertilization rate and the birth rate.


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