The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2022

Filed:

Jul. 21, 2017
Applicant:

Aiviva Biopharma, Inc., Las Vegas, NV (US);

Inventors:

Diane Tang-Liu, Las Vegas, NV (US);

Gerald Woodrow Devries, San Clemente, CA (US);

Tiffany Constance Liu, Las Vegas, CA (US);

Assignee:

AIVIVA BIOPHARMA, INC., Las Vegas, NV (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 27/02 (2006.01); A61K 9/00 (2006.01); A61K 31/47 (2006.01); A61K 31/496 (2006.01); A61K 31/438 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 9/0048 (2013.01); A61K 31/438 (2013.01); A61K 31/47 (2013.01); A61P 27/02 (2018.01);
Abstract

A method for preventing and/or treating fibrosis associated with an eye-related disease or disorder includes administering an effective amount of a multikinase inhibitor to a subject in need thereof. The multikinase inhibitor is nintedanib, lenvatinib, a combination thereof, or a salt thereof. The eye-related disease or disorder is corneal transparency, corneal scar formation, secondary cataract formation, glaucoma filtration surgery, ocular surgical procedures and implants, photorefractive keratectomy, laser in situ keratomileusis, formation and contraction of pre- and epiretinal membranes, proliferative vitreoretinopathy, subretinal fibrosis/scarring, retinal gliosis, or formation of choroidal membranes.


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