The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2022
Filed:
May. 09, 2018
Enzymaster (Ningbo) Bio-engineering Co., Ltd, Ningbo, CN;
Haibin Chen, Ningbo, CN;
Yong Koy Bong, Ningbo, CN;
Baoqin Cai, Ningbo, CN;
Qing Xu, Ningbo, CN;
Tianran Shen, Ningbo, CN;
Ameng Zhou, Ningbo, CN;
Jiadong Yang, Ningbo, CN;
Zhuhong Yang, Ningbo, CN;
Yaoyao Ji, Ningbo, CN;
Yingxin Zhang, Ningbo, CN;
Enzymaster (Ningbo) Bio-Engineering Co., Ltd, Ningbo, CN;
Abstract
The present invention provides engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The present disclosure also provides polynucleotides encoding engineered polypeptides, host cells capable of expressing engineered polypeptides, and methods of producing β-hydroxy-α-amino acids using engineered polypeptides. Compared to other processes of preparation, the use of the engineered polypeptides of the present invention for the preparation of β-hydroxy-α-amino acids results in high purity of the desired stereoisomers, mild reaction conditions, low pollution and low energy consumption. So, it has good industrial application prospects.