The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2022
Filed:
Apr. 12, 2019
Applicant:
Philogen S.p.a., Siena, IT;
Inventors:
Assignee:
PHILOGEN S.P.A., Siena, IT;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/525 (2006.01); C07K 14/55 (2006.01); C07K 16/18 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/525 (2013.01); A61K 47/6813 (2017.08); A61K 47/6851 (2017.08); A61P 35/00 (2018.01); C07K 14/55 (2013.01); C07K 16/18 (2013.01); A61K 38/00 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01); C07K 2319/75 (2013.01);
Abstract
The present application relates to conjugates comprising interleukin 2 (IL2), and a tumour necrosis factor, such as tumour necrosis factor alpha (TNFα), and an antibody molecule. The antibody molecule preferably binds to an antigen associated with neoplastic growth and/or angiogenesis, such as the Extra-Domain A (EDA) of fibronectin. The conjugate may be used in the treatment of cancer.