The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2022

Filed:

Sep. 29, 2020
Applicant:

Mammoth Biosciences, Inc., Brisbane, CA (US);

Inventors:

Janice Sha Chen, San Francisco, CA (US);

Ashley Tehranchi, San Francisco, CA (US);

Andrew Besancon Lane, San Francisco, CA (US);

James Paul Broughton, San Francisco, CA (US);

Lucas Benjamin Harrington, Berkeley, CA (US);

Maria-Nefeli Tsaloglou, San Francisco, CA (US);

Xin Miao, Mountain View, CA (US);

Clare Louise Fasching, Redwood City, CA (US);

Jasmeet Singh, Santa Clara, CA (US);

Pedro Patrick Draper Galarza, Oakland, CA (US);

Assignee:

MAMMOTH BIOSCIENCES, INC., Brisbane, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); B01L 3/00 (2006.01); C12N 9/22 (2006.01); C12N 15/113 (2010.01); C12Q 1/6816 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12Q 1/6816 (2013.01); C12N 2310/20 (2017.05);
Abstract

Described herein are devices, systems, fluidic devices, kits, and methods for detection of target nucleic acids associated with diseases, cancers, genetic disorders, a genotype, a phenotype, or ancestral origin. The devices, systems, fluidic devices, kits, and methods may comprise reagents of a guide nucleic acid targeting a target nucleic acid, a programmable nuclease, and a single stranded detector nucleic acid with a detection moiety. The target nucleic acid of interest may be indicative of a disease, and the disease may be communicable diseases, or of a cancer or genetic disorder. The target nucleic acid of interest may be indicative of a genotype, a phenotype, or ancestral origin.


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