The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2022

Filed:

Oct. 10, 2014
Applicant:

Fibralign Corporation, Union City, CA (US);

Inventors:

Catarina Hadamitzky, Hanover, DE;

Tatiana Zaitseva, San Jose, CA (US);

Michael V. Paukshto, Foster City, CA (US);

Assignee:

Fibralign Corporation, Union City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/24 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61L 27/60 (2006.01); A61K 38/18 (2006.01); A61K 35/26 (2015.01); A61K 35/16 (2015.01); A61B 18/20 (2006.01); A61F 2/10 (2006.01); A61L 27/36 (2006.01); A61L 27/50 (2006.01); A61M 5/142 (2006.01); A61M 25/01 (2006.01); A61M 27/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/24 (2013.01); A61B 18/20 (2013.01); A61F 2/105 (2013.01); A61K 35/16 (2013.01); A61K 35/26 (2013.01); A61K 38/18 (2013.01); A61L 27/3604 (2013.01); A61L 27/3641 (2013.01); A61L 27/507 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61L 27/60 (2013.01); A61M 5/14212 (2013.01); A61M 25/0194 (2013.01); A61M 27/002 (2013.01); A61L 2300/104 (2013.01); A61L 2300/25 (2013.01); A61L 2300/414 (2013.01); A61L 2300/604 (2013.01); A61L 2430/34 (2013.01); A61M 2025/0197 (2013.01);
Abstract

Materials and methods are provided to direct the formation of new lymphatics and to reconnect the disrupted lymphatic network. These materials and methods enable to improve survival of lymph nodes and lymph node fragments and their integration into a lymphatic network, following lymph node and lymph node fragments transplantation. The treatment or prevention of lymphedema is also addressed. In certain embodiments, a bundle of fibers or fibrils presented in the composition is effective to stimulate and direct the formation of new lymphatic and blood vessels. The bundle of fibers or fibrils presented in the composition is effective to promote survival of the lymph node or lymph node fragments and integration of the lymph node or lymph node fragments into a lymphatic network in the mammalian subject, at the site of transfer or transplantation.


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