The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2022

Filed:

Aug. 08, 2014
Applicants:

Cytune Pharma, Nantes, FR;

Universite Paris Descartes, Paris, FR;

Assistance Publique-hopitaux DE Paris, Paris, FR;

Inventors:

Alain Gey, Paris, FR;

Eric Tartour, Paris, FR;

David Bechard, Saint-Etienne de Montlu, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 39/395 (2006.01); C07K 14/54 (2006.01); C07K 16/28 (2006.01); C07K 14/715 (2006.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2086 (2013.01); A61K 47/6813 (2017.08); A61K 47/6849 (2017.08); C07K 14/5443 (2013.01); C07K 14/7155 (2013.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an immunomodulatory antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof; and uses thereof.


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