The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2022
Filed:
Aug. 31, 2016
Synlogic Operating Company, Inc., Cambridge, MA (US);
Vincent Isabella, Medford, MA (US);
Dean Falb, Sherborn, MA (US);
Cami Leigh Anderson, Cambridge, MA (US);
Paul Miller, Salem, CT (US);
Yves Millet, Newton, MA (US);
Jonathan Kotula, Berkeley, CA (US);
Synlogic Operating Company, Inc., Cambridge, MA (US);
Abstract
The present invention provides recombinant bacterial cells comprising at least one heterologous gene encoding at least one oxalate catabolism enzyme. In another aspect, the recombinant bacterial cells further comprise at least one heterologous gene encoding an importer of oxalate. The invention further provides pharmaceutical compositions comprising the recombinant bacteria, and methods for treating disorders in which oxalate is detrimental, such as hyperoxaluria, using the pharmaceutical compositions of the invention.