The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2022
Filed:
Nov. 03, 2016
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Stuart Aaronson, New York, NY (US);
Albino Troilo, New York, NY (US);
Davide Esposito, New York, NY (US);
Assignee:
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4409 (2006.01); A61K 31/519 (2006.01); C12Q 1/6886 (2018.01); C07K 14/47 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61K 31/551 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4409 (2013.01); A61K 31/519 (2013.01); A61K 31/551 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 14/4746 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The present invention relates to methods of treating a tumor or treating cancer in a subject having a p53 DNA contact mutation that involve administering, to the subject, a ROCK inhibitor. Also disclosed is a method of identifying a subject as a candidate for such treatment.